Pharmaceutical products contain an API( Active pharmaceutical ingredient) with compatible excipients. These two components together make the pharmaceutical drug compliant to give effects as per desire. The final/ finished product is delivered to the market so drug packaging is taken the foremost important thing to be delivered in its real and stable form. Pharmaceutical products need packaging for the preservation of their efficacy, for this purposes pharmaceutical packaging companies prefer different types of pharmaceutical packagers. Different companies make different types of pharmaceutical packaging designs to avoid plagiarism, adulteration to their products of similar others in the market, for such purpose, a pharmaceutical company designs their products and their packaging to make it different from others to maintain a uniqueness to their design in the market.
PHARMACEUTICAL PACKAGE :
Pharmaceutical packaging designs are made to give a clear, visible, and visual depiction of that medicine to the patient at a glance. A short and bold instruction can also be written on a pack to give instantly to the patient. Pharmaceutical packaging has two main integral parts with which a pharmaceutical product gets interacted. One which is to be considered a primary one is in which the drug is enclosed that might be a glass/ plastic bottle, Aluminum or paper for the blisters/sachets, depending upon the dosage form, while, the other main part is the one is considered secondary in which the product is packed and is ready to be distributed that may include paper, in the most cases, or plastics for the lamination. Thesemedicine boxes contain the information that helps the patient for their compliance to use that medicine, with many pharmaceutical products, pharmaceutical companies often design their products which contain a flyer with it, that has all the information about that medicine, such as, its indication, ingredients, pharmacological action, precautions to be taken, contraindications. A pharmaceutical pack often comes with a complimentary item with it, like, for liquids some packs may include a spoon/dropper with them for the patient's convenience.
For a drug package, that is indicative to deliver the drug has the main points to be considered are that the pack/enclosure in which the main product is filled must not interact with the API of that product, must be compatible with the environment, must not contain any contaminants, must be user friendly, must achieve a good stable shelf life of the product, must be child-resistant, tamper-resistant and tamper-evident. so for these main purposes, medicine packaging designing is considered to be most important.
For an ideal pack, pharmaceutical packaging design is done to be ultimately tamper-proof, which means that it must ensure that no material is taken out or added into it. Drug absorption/adsorption must be none to its pack surface, because it may reduce the efficacy and potency of the API in which the product is being dealt in.
Pharmaceutical packaging is selected based on the dosage form and also on the route of administration. For a better delivery of a drug, drug/pill packaging is often designed to deliver all of the product without being deteriorated, for this, testing is done at each end to make sure that the drug package will be safe and stable enough throughout its shelf life. To maintain its efficacy, certain tests, such as stability testing, quality control, and assurance tests are done and after that, a potent expiry date is given to that product. A pharmaceutical pack may directly deliver the dose, as a single / multi-unit dose. Single/ unit dose packages are sachet packs, blister packs, single strip packs. On the other hand, multi-dosing includes packs of vials, ampoules, blisters with multi-dosing, bottles.
Other than the product, now focusing on the packing material. Selecting packing material depending upon the basis of the nature of the product is also a necessary part. For the selection of the fittest packing material, the nature of the pharmaceutical product and its main ingredients must be known. Ideal medicinal packaging requires the main points to be considered, such as drug stability profile, compliance to the patient, chemical and physical features of the product, environmental and eco-friendliness. Different forms of pharmaceutical packs need a different kind of care. Like, Injectable requires regular and most keen visual observations and chemical testings to maintain its potency and free from other foreign contaminants from the environment. Whereas, solids/liquids as compared to injectables require less physical examination but, it is necessary to keep a close eye on its chemical testings because delivering a pharmaceutical product to a market if dealing with human lives directly. Semisolids require slightly different care comparing to others, it needs to be delivered under pressure to the closure, such as delivering a medicinal product in a tube.
For maintaining the stability of a product, the properties of its ingredients must be very much known. If a product is resistant or intolerant to the environment particularly sunlight and the drug package is delivered without caring for this feature then it may deteriorate the function, potency, and efficacy of the pharmaceutical product. So for maintaining the high-end stability of the product, we have to use such packaging material whether primary/secondary, that eliminates the penetration of sunlight to the product.
Pharmaceutical packaging companies often use Glass, Plastics, Rubbers, Elastomers, Metals, Paper, and Laminates, depending on the route of administration and nature of the delivering pharmaceutical product. All the products that are used have pros and cons. So keeping assured of the delivery of the medicine box it's kept.
REPACKING OF THE PRODUCT :
The product is often packed by the manufacturers and is delivered to the patient. But in some cases, it often needs repacking of the original product into other than original pill packaging. It is done mostly to a small extent often at hospitals, community pharmacies, and /or for distribution purposes. Repackaging is considered to be done legally and It is done mostly by pharmaceutical packagers and for the oral solid dosage forms keeping it clear from the stability, cross-contamination, potential legal aspects, and other hazards point of view.